N-Acetylglutamic acid (also referred to as N-acetylglutamate, abbreviated NAG, chemical formula C7H11NO5) is biosynthesized from glutamate and acetylornithine by ornithine acetyltransferase, and from glutamic acid and acetyl-CoA by the enzyme...
The urea cycle (also known as the ornithine cycle) is a cycle of biochemical reactions that produces urea (NH2)2CO from ammonia (NH3). Animals that use this cycle, mainly amphibians and mammals, are called ureotelic. The urea cycle converts highly...
The organic compound citrulline is a non-essential α-amino acid. Its name is derived from citrullus, the Latin word for watermelon. Although named and described by gastroenterologists since the late 19th century, it was first isolated from...
N-Acetylaspartic acid, or N-acetylaspartate (NAA), is a derivative of aspartic acid with a formula of C6H9NO5 and a molecular weight of 175.139. NAA is the second-most-concentrated molecule in the brain after the amino acid glutamate.
Glutamate N-acetyltransferase (EC 2.3.1.35) is an enzyme characterised from Chlamydomonas reinhardti that is involved in the biosynthesis of arginine by catalyzing the chemical reaction The two substrates of this enzyme are N-acetylornithine and...
Aceturic acid (N-acetylglycine) is a derivative of the amino acid glycine. The conjugate base of this carboxylic acid is called aceturate, a term used for its esters and salts.
N-Acetylglutamate synthase deficiency is an autosomal recessive urea cycle disorder.
Lactoylphenylalanine, or Lac-Phe, is an N-lactoyl-amino acid metabolite produced by mammals and microorganisms. In humans, levels are increased by intense exercise and in the inborn error of metabolism phenylketonuria. In mice, high levels of...
Acetylglutamate kinase (EC 2.7.2.8) is an enzyme that catalyzes the chemical reaction: The enzyme characterised from the bacterium, Escherichia coli and the green algae, Chlamydomonas reinhardti, converts N-acetyl-L-glutamic acid to...
Pivagabine (INN; brand name Tonerg), also known as N-pivaloyl-γ-aminobutyric acid or N-pivaloyl-GABA, is an antidepressant and anxiolytic drug which was introduced in Italy in 1997 for the treatment of depressive and maladaptive syndromes. But it...
